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Madeline Bell, CEO of the renowned Children’s Hospital of Philadelphia, takes you behind the scenes to meet the brilliant minds who are making - and supporting - incredible breakthroughs in pediatric medicine.
Madeline Bell, CEO of the renowned Children’s Hospital of Philadelphia, takes you behind the scenes to meet the brilliant minds who are making - and supporting - incredible breakthroughs in pediatric medicine.
Episodes

Friday Aug 22, 2025
Advancing Gene Therapy: KJ’s Story
Friday Aug 22, 2025
Friday Aug 22, 2025
Earlier this year, baby KJ became the first patient in the world to receive a personalized gene editing therapy, which was developed by a team at Children’s Hospital of Philadelphia (CHOP) and Penn Medicine. In June, KJ went home after spending more than 300 days at CHOP. On this episode of Breaking Through, Madeline speaks to KJ’s parents, Kyle and Nicole, about the treatment that changed KJ’s life – and how he’s doing today.

7 months ago
What an outstanding journey for KJ and the family! Strength through hope and courage, and a Great care team from PENN & CHOP made a remarkable breakthrough for KJ. Kudos to all involved!